Mortality in Hypopituitarism Causes Clinical Features Diagnosis and Endocrine Assessment Treatment of Hypopituitarism Strategies to Prevent Hypopituitarism

Hypopituitarism is the deficiency of one or more pituitary hormones. It is relatively rare, with a prevalence of 45 per million and an annual incidence of about 4 per 100,000.1 It is, however, seen commonly in endocrine practice and, importantly, is associated with increased morbidity and mortality. Clinical manifestations are influenced by the etiology, severity, and rate of onset of pituitary hormone deficiency.